Group of Dr. Hana Cahová Chemical Biology

News

We are happy to share that our work on Ap2N-capped RNAs has been published in PNAS!
Lab retreat 2026
We Welcomed the President of the Czech Republic to Our Laboratory
Big congratulations to Valentina Serianni, Anton Skriba, and all co-authors on this fantastic new publication!
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Publications

Valentina M. Serianni, Jana Škerlová, Anna Knopp Dubánková, Anton Škríba, Hana Šváchová, Tereza Vučková, Anatolij Filimonenko, Milan Fabry, Pavlína Řezáčová, Tomáš Kouba & Hana Cahova

Molecular insight into 5′ RNA capping with NpnNs by bacterial RNA polymerase
Nature Chemical Biology 2026 https://doi.org/10.1038/s41589-025-02134-5

Stanislav Stejskal, Veronika Rájecká, Helena Covelo-Molares, Ketty Sinigaglia, Jana Melicherová, Shwetha Krishna, Pavla Linhartova, Linda Kasiarova, Paul Eduardo Reyes-Gutierrez, Hana Cahová, Angela Gallo, Ales Obrdlik, Liam P. Keegan, Mary A. O’Connell, and Stepanka Vanacova

Global analysis by LC-MS/MS of N6-methyladenosine and inosine in mRNA reveal complex incidence
RNA 2025 10.1261/rna.080324.124

Pavel Vopalensky, Anton Škríba, Michela Chiumenti,  Lucia Ďuričeková, Anna Šimonová, Ondřej Lukšan,  Francesco di Serio,  Beatriz Navarro,  Hana Cahova

Exploring RNA modifications in infectious non-coding circular RNAs
RNA biology 2025 https://doi.org/10.1080/15476286.2025.2459039

Flaminia Mancini & Hana Cahova

The Mysterious World of Non-canonical Caps – What We Know and Why We Need New Sequencing Techniques
ChemBioChem 2024 https://doi.org/10.1002/cbic.202400604
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Support

IOCB PragueThe Czech Academy of SciencesMinistry of Education, Youth and SportsEuropean Research Council